会议日程

 Day 1    Thursday, November 7
08:45-08:55 Opening   Organizer’s Remarks
08:55-09:00 Chair Ekkehard Leberer, PhD
09:00-09:45 Keynote

RNA Guided Genome Surveillance

Craig Mello, PhD, Professor, UMass Medical School, 2006 Nobel Prize in Physiology or Medicine, USA

09:45-10:20

Understanding and Applying RNAi in Mammalian Cell Nuclei

David Corey, PhD, Rusty Kelley Professor of Medical Sciences, UT Southwestern Medical Center, USA

10:20-10:50 Refreshment Break & Poster Session
10:50-11:25

 Driving in the Dark: Hunting for Long Noncoding RNAs in Cancer

Rory Johnson, PhD, Department of Medical Oncology, University Hospital of Bern, Switzerland

11:25-12:00

Biomimetic Chemistry of RNAi Therapeutics

Muthiah Manoharan, PhD, Senior Vice-President, Alnylam Pharmaceuticals, USA

12:00-13:30 Buffet Lunch
13:30-13:35 Chair   Xiaohu Gao, PhD
13:35-14:20

Special

Invited Talk

Structural Biology of CRISPR-Cas Surveillance Complexes

Dinshaw Patel, PhD, Member of the American Academy of Arts and Sciences, USA

14:20-14:55

Biological Robustness: Genetic Compensation and Transcriptional Adaptation

Didier Stainier, PhD, Director, Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Germany

14:55-15:25 Refreshment Break & Poster Session
15:25-16:00

Deciphering the ‘m6A code’ via Quantitative, Antibody Independent Mapping

Schraga Schwartz, PhD, Group leader, Department of Molecular Genetics, Weizmann Institute of Science, Israel 

16:00-16:35

Targeted Intracellular Delivery of siRNA

Xiaohu Gao, PhD, Professor of Bioengineering, University of Washington, USA

16:35-17:10

Functions and Modes of Action of Long Noncoding RNAs in Mammalian Cells

Igor Ulitsky, PhD, Senior Scientist, Department of Biological Regulation, Weizmann Institute of Science, Israel

17:10 End of Day 1
Day 2    Friday, November 8
08:55-09:00 Chair  Muthiah Manoharan, PhD
09:00-09:45 Keynote The Molecular Logic of Neural Circuit Formation

Thomas C. Südhof, M.D., Professor, Stanford University School of Medicine, 2013 Nobel Prize in Physiology or Medicine, USA

09:45-10:20 MiRNA Therapeutics: From Discovery to the Bedside

Ekkehard Leberer, PhD, Senior Director of R&D Alliance Management, Sanofi, Germany

10:20-10:50 Refreshment Break & Poster Session
10:50-11:25 Functional Characterization and Therapeutic Targeting of Gene Regulatory Elements

Nadav Ahituv, PhD, Professor, Institute for Human Genetics, University of California San Francisco, USA

11:25-12:00 Tech Report GE Healthcare
12:00-13:30 Buffet Lunch
13:30-13:35 Chair   Bryan C. Dickinson, PhD
13:35-14:10   The Role of tRNA Derived Small RNAs in Gene Regulation – A Potential Target for a New Cancer Therapeutic

Mark A. Kay, PhD, Professor, School of Medicine, Stanford University, USA

14:10-14:45 Humanized Synthetic Biology Approaches to Exploit RNA Regulation

Bryan C. Dickinson, PhD, Associate Professor of Chemistry, University of Chicago, USA

14:45-15:20 Gene Regulation Mediated by Non-coding RNAs, RNA Binding Proteins and RNA Modifications 

Gunter Meister, PhD, Professor and chair of Biochemistry, University of Regensburg, Germany

15:20-15:55 Targeting RNA sequences and structures with a PNA-based programmable platform

Gang Chen, Assistant Professor, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore

15:55-16:30 Tech Report TBD
16:30 Closing Craig Mello, PhD, Professor, UMass Medical School, 2006 Nobel Prize in Physiology or Medicine, USA

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